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Fig. 2. Properties of dominant-negative mutant EcRs used in this paper. Sequences are shown only for the region around helix 12 of the LBD; residue numbers are for isoform EcR-B1. Bold type indicates strongly conserved residues; mutated residues are boxed. Functional assays are described by Hu et al. (X. H., L. C. and P. C., unpublished).





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