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Fig. 5. Effects of targeted expression of individual EcR isoforms in the presence
of EcR-F645A. Flies homozygous for both the EcR-F645A responder and a
responder corresponding to the indicated wild-type EcR were crossed to each
driver stock. EcR-C was not tested with the act5C and EH drivers. All other
combinations of drivers were tested; if no bar is visible, there were no
progeny with wild-type phenotype. For the EH driver, wild-type phenotype is
expanded wings; for the other drivers, wild-type phenotype is survival to
adulthood. In the case of the GMR driver, wild-type EcR isoforms restored
wild-type eye morphology as well as viability (see Fig. 5C). Data are shown
for crosses performed at 25°C, but the results were independent of
temperature (data not shown).
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