Fig. 4. Hh signal from posterior A9 induces En and Ptc expression in the most anterior part of A10-11. (A,B) Overexpression of Hh in the En domain of A9 using en-Gal4/UAS-hh expands (double arrow) Ptc (green, A) and En (green, B) expression and causes a reduction (double arrow) in Cad (red) expression in the most anterior part of A10-11. (C,D) smo^- clones (which do not receive the Hh signal) in the most anterior part of A10-11 segment fail to express either Ptc (C) or En (D). A10-11 is labelled by the expression of Cad (blue). The smo^- clones (thicker outline) and associated twin cells (thinner outline) are marked by ß-gal (C) or GFP (D) expression (green).

Return to article