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Fig. 5. Target sequences of Dnmt2-mediated DNA methylation. Methylated sequences were identified in Drosophila DNA by bisulfite sequencing of random genomic fragments. This revealed that overexpression of Dnmt2 results in specific methylation at CpT and CpA dinucleotides. Methylated cytosine residues are shown in red and their 3'-neighbours are indicated in green.





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