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Fig. 6. Distinct pathways involved in HOB gene regulation. Transcriptional
regulation by egl-44 and egl-46 directs a cell-specific
pathway necessary for HOB function in vulva location behavior. In the general
ciliogenic pathway, the RFX-transcription factor DAF-19 controls expression of
cilium structural genes to provide functional compartment common for all
ciliated sensory neurons. DAF-19 has an additional influence on HOB neuronal
function by affecting expression of downstream genes in the HOB-specific
pathway through some unknown factor(s), indicated by Y. Genes in the shadowed
box are the ones in which the Lov phenotype were analyzed in mutants
(Barr and Sternberg, 1999)
(this work). There are no existing mutants for ceh-26 and
nlp-8.