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Fig. 4. Condensed alveolar structures in biparous Erbb4Flox/FloxWap-Cre mice. Histological analysis of Hematoxylin and Eosin stained paraffin wax-embedded biparous Erbb4+/+Wap-Cre (A,C,E) and Erbb4Flox/FloxWap-Cre (B,D,F) mammary glands at P13.5 (A,B), P18.5 (C,D) and L1 (E,F). Abnormal secretory activity is indicated by the accumulation of lumenal lipids in Erbb4Flox/FloxWap-Cre mammary glands at parturition. Arrowheads indicate alveolar lumens. Scale bar: 50 µm.





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