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Fig. 9. Expression of FMRFa in neuroendocrine cells enables wit mutants to eclose without rescuing the primary defects in synaptic transmission or synapse morphology. (A) Wild-type Oregon R. (B-D) Partial rescue of wit adults in which FMRFa is expressed in neuroendocrine cells using the C929 driver (w; P{UAS>FMRFa, w+}/P{C929>Gal4, w+}; witA12, st/witB11, st). (B) Partial eclosion, (C) full eclosion but no wing inflation, and (D) full eclosion and full wing inflation. (E) Lack of wing inflation in adult expressing {Delta}Gl in neuroendocrine cells. (F) Wild-type synapse at muscles 6/7 visualized by anti-Csp staining. (G) Small synapse at muscles 6/7 of witA12/witB11 animals expressing FMRFa with the C929 driver. (H) Representative traces of evoked junctional potentials of wild type, wit mutant and wit mutant expressing FMRFa. (I) Histogram representation of 5 recordings. Scale bar: 20 µm.





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