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Fig. 8. Regulation of ectopic activation of Nodal target genes by bon and sur. (A-L) squint RNA was injected in different genetic backgrounds and assayed for gene activation at 50% epiboly. (A-D) gsc is induced in bon (B) and MZsur (C) but not in MZsur;bon mutants (D). (E-H) cas is induced in MZsur (G) but not in bon (F) and MZsur;bon (H) embryos. (I-L) bik is induced in bon (J) and MZsur;bon and MZsur;bon/+ (J and not shown) but not in MZsur (K) mutant embryos.





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