Fig. 7. MEL-11 is dependent on LET-502 for its localization. Although only low levels of cytoplasmic anti-MEL-11 staining was present in the lateral epidermal cells of wild type (A), higher cytoplasmic levels were present in let-502(ca201) (B), which arrests at the onset of elongation. let-502(sb106) embryos undergo elongation, albeit abnormally, and also show higher levels of cytoplasmic MEL-11 (C). The let-502(sb106) embryos in D is at a later stage than that in C, and again showed higher levels of cytoplasmic MEL-11 compared with wild type (A). The embryo in D presents a more ventral aspect; the posterior lateral epidermal cells indicated by the bracket were in the focal plane and show increased cytoplasmic MEL-11. All images were deconvolved. Scale bar: 10 µm.

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