Fig. 8. Transplants suggest that low^ts213 functions cell autonomously in neural crest. Prospective hyoid arch neural crest and hindbrain cells at the level of rhombomeres 4 and 5 (r4 and r5) were transplanted from donor embryos labeled with a lineage tracer (red) into unlabeled hosts at 12 hpf (A-C). Lateral views (A'-C') and ventral views (A''-C'') of mosaic larvae at 65 hpf stained for biotinylated tracer (brown). (A-A'') Control transplants between wild-type embryos. (B-B'') Wild-type transplants into low mutants. Arrow indicates rescued hyoid arch outgrowth on the transplanted side. (C,C') Transplants of low mutant crest cells into wild-type hosts. (B''') Rescued muscles of the hyoid arch in low mutants containing transplanted wild-type neural crest. am, adductor mandibulae muscle; P2, pharyngeal arch 2 (hyoid arch). Scale bars: 100 µm.

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