Fig. 5. Distribution and morphology of GFP⁺ neurons in a transgenic mouse homozygous for the Gad67-GFP allele (Gad67^gfp/gfp). (A,B) GFP⁺ neurons in fixed sections of the dorsal cortex from an E13.5 (A) or an E15.5 (B) homozygous (Gad67^gfp/gfp) mouse embryo. There is no notable difference in distribution and morphology of GFP⁺ neurons between heterozygous (Gad67^gfp/+) and homozygous (Gad67^gfp/gfp) mice (compare with Fig. 1B,C). As in heterozygous mice, many neurons with a leading process are found in the lower IZ. (C,D) Quantitative representation of GFP⁺ migrating cells from an E13.5 homozygous mouse. There is no noticeable difference in direction or average speed between heterozygous and homozygous mice (compare with Fig. 4A,C). Scale bar: 50 µm.

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