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Fig. 1. Representative pyramidal neurons from layers II/III, V and VI transfected with EGFP, BDNF/EGFP and NT4/5/EGFP. (A) Neurons of the early time window, DIV 0-5. Only layer VI neurons displayed more profuse dendritic trees. (B) Neurons of the later time window, DIV 5-10. Now BDNF and NT4/5 strongly accelerated the development of apical and basal dendrites. Note that neurotrophin transfectants at 5 DIV appear quite similar to EGFP control transfectants at 10 DIV.





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