Fig. 9. Ectopic btd activity in wing induces spatially discriminated expression of leg developmental markers. (A) Large btd-expressing clone (blue) induces hth activity (green), but only on the periphery (B), resembling the disposition of the normal leg disc. (C) Another btd-expressing clone showing non-homogenous gain of Dll and dac activity: all cells express Dll (red) but only about half gain dac (green, D). (E) Another clone (arrow) showing a spatial deployment of dac and Dll resembling closely that along the PD axis in the normal leg (F): dac activity alone (green), dac and Dll (yellow), and Dll only (red). In the normal leg, these patterns of gene expression would correspond to the positions of the femur, tibia and tarsus, respectively.

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