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Fig. 7. Sex transformations caused by mutating Hh pathway components and inhibition of Hh signaling by overexpression of Sxl. (A-E) Forelegs of wild-type male (A) and female (B) and of females with PKAH2 (C), cos2w1 (D) and ptcS2 (E) clones. Arrows indicate slightly thickened bristles in legs with mutant clones, particularly cos2w1 (females normally lack thickened bristles). (F-H) Wing from wild-type female (F) and female expressing Sxl in dpp expression zone (G,H). Note difference in spacing between wing veins L3 and L4 (arrows in G) as well as the hairs at the wing margin (arrowheads), which are characteristic of the anterior compartment.





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