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Fig. 2. Tail and inner ear phenotype of Fgf3–/– mutants. (A) Fgf3–/– adult mutants show a shortened, thickened and kinked tail. (B,C) Sections through the otic vesicle of a wild-type and a Fgf3–/– mutant littermate at E10.75. The endolymphatic duct is indicated by an asterisk. Note the reduced size of the otic vesicle in the mutant embryo compared with the wild-type control animal. (D,E) Transverse sections through the inner ear at E13.5. The cochleovestibular ganglion (cvg), endolymphatic duct (ed) and posterior semicircular canal are indicated (pc). (F,G) Sections through the cochlea of wild-type and Fgf3–/– adult mutant littermates. The cochlear ganglion is indicated by arrows. Scale bars: in C, 200 µm for B,C,F,G; in D, 200 µm for D,E.





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