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Fig. 3. Loss of function of L suppresses ventral eye development. (A) L mutant disc showing loss of ventral eye pattern. Loss-of-function clones of L were marked by absence of GFP (green) in the eye disc (B) and by absence of white gene expression in adult eye (C). Eye discs were stained for 22C10 or Elav. Clone in the dorsal eye shows no effect on eye fate in disc (B,B', arrow). Ventral clone caused suppression of eye fate as seen by absence of 22C10 in disc (B,B', arrowhead) and in adult (C, arrow). (D,D') Ventral loss-of-function clone of L also showed ectopic induction of Ey where eye fate is blocked (arrowhead). (E,E') Early loss-of-function clone of L showed complete elimination of eye fate as evident by absence of Elav (red). Note that eye field (EYE) is highly reduced, whereas antennal (AN) development was not affected.





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