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Fig. 2. The C-terminal domain of DPY-21 is conserved between species. In the
alignment of the C terminus (amino acids 1224-1641), black indicates sequence
identity, and gray represents sequence similarity. DPY-21 contains no
identifiable motifs. However, the C-terminal region of DPY-21 appears to be
conserved throughout evolution. No other significant similarity was found
between DPY-21 and the putative homologs, as they are rendered in current data
bases. The function of these DPY-21 homologs has not been determined.
Locations of dpy-21 mutations are indicated by the +
symbol.
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