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Fig. 3. Cortical neurotrophins accelerate development of LGN neurons. Medians of contralateral (white circles) and ipsilateral (black circles) LGN were compared at P20 (NT-4/5, n=2), and P28 (NT-4/5 and NGF, total n=7) and at P45 (NT-4/5, combined n=4 plus n=2 untreated P45 animals). NT-4/5 and NGF data were pooled, because both factors elicited the same highly significant size shifts (compare Fig. 1C with 1D). Contralateral somata progressively reach the adult size whereas ipsilateral somata reach adult sizes prematurely because of NT-4/5 and NGF infusions.





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