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Fig. 1. ft and ds regulate planar polarity. (A) Wild-type dorsal (D) and ventral (V) ommatidia. At the five-cell stage, preclusters rotate in opposite directions to assume D and V polarity. Outer photoreceptors are recruited into the clusters as pairs and share similar characteristics, indicated by similar colors in the R1/6, R2/5 and R3/4 cells. Dorsal is upwards and anterior is leftwards. (B) Smooth edges of mitotic clones of ftAlbert (arrows). All ft alleles examined had smooth edges, planar polarity defects and enhanced growth in clones. (C-E') Sections (C-E) and schematic diagrams (C'-E') of wild-type, and ft and ds mutant fly eyes. In the wild-type eye (C,C') the trapezoid shapes formed by the photoreceptor rhabdomeres of the D ommatidia point upwards (red arrows), the V ommatidia (blue arrows) point in the opposite direction; D and V fields are separated by a division known as the equator (yellow line). In ftfd/ftchance transheterozygous (D,D') and dsUAO71 homozygous mutants (E,E'), D and V ommatidia are intermixed and no obvious equatorial line can be drawn. (F,G) Sections of ftfd and dsUAO71 mutant clones and (F',G') diagrams of PP. ft- and ds- tissue are marked by the absence of pigment. White arrows indicates wild-type ommatidia on the polar (F) or equatorial (G) sides of the clones, non-autonomously affected by the clones. Red and blue arrows (F',G') indicate ommatidia with D and V polarity, respectively, in these and in all remaining panels.





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