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Fig. 10. Cells intercalate mediolaterally in both the wild-type and ntl
mutant embryo (A,B), but only during brief intervals in the mutant, when
compared with the wild type (C). (A) Intercalating cells become neighbors
(blue, neighbor gains), pushing apart old neighbors (red, neighbor losses).
Hence, for cells undergoing MIB, neighbor gains are ML (horizontal in the
diagram) and neighbor losses AP (vertical; see also
Fig. 2). (B) The polar plots
show that these predicted behaviors are observed; the distributions are
evidently broadened for the mutant. All four distributions are nonrandom
(P<0.05; Watson's U2n test). The
distributions are based on 623 gains and 633 losses for the wild type, and
1473 gains and 1822 losses for the mutant. (C) Colored bars show the durations
of time periods when neighbor gains and losses are significantly oriented
along any axis (Watson's test for nonrandom data). In the wild type, these
periods of highly oriented activity are sustained during most of the time
interval sampled. In the mutant, pulses of oriented and random behaviors are
interspersed.