Fig. 5. Increased number of semi-innervated P2 glomeruli in transgenic mice. Quantification of glomeruli in control and transgenic mice. P2 axons were visualized by ß-galactosidase staining and innervated glomeruli were counted manually. (A) Graph represents total number of major P2 glomeruli/olfactory bulb in control (cont) (n=36), GpiRNCAM (Gpi) (n=42) and TmRNCAM (Tm) (n=26) transgenic animals. Control and transgenic mice had the same number of major glomeruli. (B) Graph represents total number of semi-innervated P2 glomeruli/olfactory bulb in control mice (cont) (n=36), GpiRNCAM (Gpi) (n=42) and TmRNCAM (Tm) (n=26) transgenic animals. Both GpiRNCAM and TmRNCAM transgenic mice showed a significant increased number of semi-innervated P2 glomeruli. Results are mean±s.e.m. (^***P<0,0001, Student's t-test). The data were obtained from progeny of two transgenic founder lines transgenic for each RNCAM isoform.

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