Fig. 1. Laterality of the pineal complex. The zebrafish pineal complex consists of the pineal organ and the parapineal (black arrowhead), which both express otx5 (blue). (A,B) The parapineal lies to the left of the pineal anlage at 2 d, at the same dorsal level as the pineal, but (C,D) becomes more caudally and ventrally located during larval development. (E) In a frontal view of a 15 d larval brain, the parapineal lies in a more ventral position relative to the pineal. (F) In the adult brain, the parapineal is found at the base of the pineal stalk (arrow), next to the left habenula (Lh). (A,C,F) Dorsal views; (B,D) cross-sections counterstained with basic fuchsin (pink). Rh, right habenula. Scale bars: 50 µm for A-E; 150 µm for F.

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