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Fig. 1. Visualisation of SPUs in H253 female hemizygotes. Specimens are stained
with X-Gal to reveal ß-galactosidase-positive (blue) cells. (A) The colon
at 12 weeks of age, showing monoclonality of crypts. (B) The skin, epidermal
wholemount viewed from exterior surface showing columns of blue cells
extending through the epidermis.
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