Fig. 5. Neurons at the anterior end of the Fgfr1-deficient telencephalon make connections characteristic of mitral cells. DiI labeling of sensory axons from the olfactory epithelium (oe) at E12.5 shows that axons have reached the anterior telencephalon (tel) in both control (A) and Fgfr1-deficient (A') mice. Scale bar: 0.1 mm. (B,B') DiI labeling of the olfactory epithelium (oe) at E18.5 reveals that sensory axons have penetrated the anterior telencephalon in both control (B) and mutant (B') mice; ventricular and basal borders of the telencephalic neuroepithelium are indicated (broken lines). Scale bar: 0.15 mm. (C) Retrograde labeling of mitral cells in the olfactory bulb of control mice following DiI injection into lateral (piriform) cortex (in which DiI penetrated the tract). Similar cells are labeled in Fgfr1 mutants (C'). Scale bar: 0.1 mm.

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