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Fig. 5. dap is required to maintain oocyte fate. (A,B) Wild-type and (C-F) dap4 clones double labeled with DAPI (A,C,E) to highlight nuclei and {alpha}BicD antibody (B,D,F). Note that in D, where the dap4 oocyte has become highly polyploid, there is little preferential accumulation of the BicD protein. By contrast, in F, where the dap4 oocyte has undergone little to no DNA replication, BicD accumulates to levels similar to those observed in wild-type oocytes.





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