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Fig. 5. Interaction between Dock and Pak is necessary for antennal lobe development. ALs of adult dockP1/dockP1 mutants, expressing wild-type and various mutant UAS-dock cDNA constructs under the control of SG18.1-Gal4, were stained with nc82 mAb to assess AL development. (A) Wild-type dock cDNA: UAS-dockWT; dockP1/dockP1. (B) No cDNA: dockP1/dockP1. (C) Mutation in the first SH3 domain: UAS-dockW48K; dockP1/dockP1. (D) Mutation in the second SH3 domain: UAS-dockW151K; dockP1/dockP1. (E) Mutation in the third SH3 domain: UAS-dockW225K; dockP1/dockP1. (F) Mutation in the SH2 domain: UAS-dockR336Q; dockP1/dockP1. Scale bar: 25 µm.





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