Fig. 6. Loss of DRI results in downregulation of Neuroglian in subsets of longitudinal glial cells. Whole-mount immunochemical staining of wild-type (A-C) and dri¹/dri² (D-F) embryos. Dorsal glial cells are labelled with Pß-gal (driven by a gcm enhancer trap, green) and mAb 1B7 against NRG CAM (red). In all panels anterior is upwards. LG are slightly misplaced in some hemisegments. Some of those cells do not express Neuroglian and show a rounded cell shape (arrows in D,F indicate cells shown at higher magnification in inset), although the penetrance is low, the phenotype being detected on average in three hemisegments from T1 to A8 in an embryo.

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