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Fig. 4. Expression of crystallin genes and retinal differentiation marker genes in Mab21l1+/- and Mab21l1-/- embryos. In situ hybridization of paraffin wax sections at E12.5 (A-D) and E15 (E-H). Expression of: {alpha}A-crystallin in Mab21l1+/- (A) and Mab21l1-/- (B) embryos; {gamma}A-crystallin in Mab21l1+/- (C) and Mab21l1-/- embryos (D); Chx10 in Mab21l1+/- (E) and Mab21l1-/- (F) embryos; and Brn3b in Mab21l1+/- (G) and Mab21l1-/- (H) embryos. Arrowheads (B,D) indicate crystallin distribution in an Mab21l1-/- embryo. Scale bars; 100 µm for A-D; 200 µm for E-H.





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