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Fig. 8. Interneurons migrate to the cortex in Slit1;Ntn1 and
Slit1;Slit2;Ntn1 mutants. Coronal sections through the telencephalon
of E18.5 fetuses showing calbindin immunohistochemistry in wild-type (A,B) and
Slit1;Ntn1 (C,D) mutant mice. (B,C) High magnification photographs of
the regions boxed in A and D, respectively. (E,F) Nissl staining of from
sections adjacent to B and C, respectively. (H-K) Coronal sections through the
telencephalon of E18.5 embryos showing expression of GAD67 (H,J) and
Lhx6 (I,K) in Slit1 (H,I) and Slit1;Slit2;Ntn1
(J,K) mutant mice. cc, corpus callosum; cp, cortical plate; GP, globus
pallidus; H, hippocampus; hc, hippocampal commissure; iz, intermediate zone of
the cortex; mz, marginal zone of the cortex; NCx, neocortex; PB, Prost bundle;
PCx, piriform cortex; POa, preoptic area; S, septum; Str, striatum; Scale
bars: 300 µm (A and D); 200 µm (B, C, E, and F); 500 µm (H-K).
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