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Fig. 3. Absence of the Brca1 full-length isoform results in p53-dependent and p53-independent apoptosis. Percentages of seminiferous tubules containing TUNEL-positive cells (A) and percentages of TUNEL-positive cells (B) at P10, P16 and P21 in p53+/- and Brca1{Delta}11/{Delta}11p53+/- testes. TUNEL-positive cells in Brca1{Delta}11/{Delta}11p53+/+ (P19) (C), Brca1{Delta}11/{Delta}11p53+/- (P21) (E) and Brca1{Delta}11/{Delta}11p53-/- (P21) (G) testes. Corresponding H&E-stained histological images are shown in D,F,H.





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