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Fig. 4. Expression of gdnf receptor components in cranial ganglia and
brain. Lateral views (A-D) and dorsal views (E-H) of 24 hpf (A,C) and 48 hpf
(B,D-H) embryos. At 24 hpf, gfra1a (A) is expressed in lateral line
ganglia, while gdnf (C) is expressed in the migrating lateral line
primordium (arrow). At 48 hpf, gfra1a (B) is expressed in
epibranchial ganglia, while gdnf (D) is expressed in pharyngeal
pouches (arrows). gfra1a (E), gfra2 (F), ret (G)
and th (H) are shown at 48hpf. Black arrowheads indicate the ventral
diencephalic neurons, red arrowheads indicate dorsal diencephalic neurons,
white arrowheads indicate the ventral midbrain neurons, pink arrowheads
indicate trigeminal motor nucleus, green arrowheads indicate anterior
hindbrain domain. all, anterior lateral line ganglia; pll, posterior lateral
line ganglia; llp, lateral line primordium; gV, trigeminal ganglia; gVI,
facial ganglion; gVIII, octaval/statoacoustic ganglion; gIX, glossopharyngeal;
gX, vagal ganglion; DiC, diencephalic catecholaminergic cell cluster; LC,
locus coeruleus; sym, sympathetic neurons.
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