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Fig. 2. Increased GLP-1/Notch signaling inhibits GLD-1 accumulation. Hermaphrodite gonad arms, with distal to the left, stained with (A-C) DAPI (blue), (D-F) REC-8 antibodies (proliferative cells; green) and (G-I) GLD-1 antibodies (red). (A,D,G) Wild-type young adult; (B,E,H) unc-32(e189) glp-1(oz112gf)/unc-36(e251) glp-1(q175); (C,F,I) dpy-19(e1259) unc-32(e189) glp-1(oz112gf)/dpy-19(e1259) unc-32(e189) glp-1(oz112gf); qDp3 [qDp3 contains unc-32(e189) and wild-type copies of dpy-19 and glp-1 (Austin and Kimble, 1987)]. Scale bar: 20 µm.





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