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Fig. 6. dMyc induced growth and endoreplication is blocked by Cyclin E and cdk overexpression but only partially by loss of PI3K activity. (A-P) DAPI stained salivary glands with attached fat body (FB) from wandering third instar larvae with or without (control) the indicated transgenes driven by ptc-Gal4. (I-P) Nuclei double stained with DAPI (blue) and anti-fibrillarin (green) are shown at higher magnification. Numbers in the lower right corner (A-H) indicate the ratio of median DAPI fluorescent intensity of posterior salivary gland nuclei to a single fat body nucleus.





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