|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 4. Quantification of oligodendrocyte marker gene expression in the spinal cord
of mice carrying Sox8 and Sox10 null alleles. The number of
Olig2-positive cells (A,B), Plp-positive (white bars) or Mbp-positive (black
bars) cells (C,D) was determined at 18.5 dpc (A,C) and postnatal day 3 (B,D)
in wild-type (+/+), Sox8lacZ/lacZ,
Sox10+/lacZ and Sox8lacZ/lacZ,
Sox10+/lacZ spinal cords, as indicated below the bars. At
least 15 separate 20 µm sections from the forelimb region of two
independent embryos were counted for each genotype. Data are presented as
mean±s.e.m. Differences from the wild type were statistically
significant for all mutant genotypes in C,D, as determined by Student's
t-test (P
0.001).
|
