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Fig. 5. Neuronal patterning defects in moz mutants. (A-D) Cranial motoneurons labeled by Islet1:GFP (Higashijima et al., 2000) at 48 hpf in wild type (A,C) and moz mutants (B,D). (A,B) Most moz mutants (52%, 11 of 21) show defects in cell body positioning of facial motoneurons (arrow). (C,D) Cranial nerves innervate each pharyngeal arch in moz mutants. The VIIIth nerve octavolateralis efferent (arrowheads in C,D) is variably mispatterned in moz mutants, resembling the phenotype seen in hoxb1a-MO injected larvae (McClintock et al., 2002).





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