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Fig. 6. Lmx1a cell-autonomously inhibits formation of dI1 interneurons. (A-H) Chick spinal cord expressing Lmx1a-IRES-EGFP 48 hours after electroporation. Visualization of expression of LH2A/B (A), Lim 1/2 (C), Islet 1 (E) and Cath1 (G) (all red) alone or together with GFP (green) (B,D,F,H). Insets show higher magnifications of boxed regions. Arrowheads point to yellow cells co-expressing exogenous Lmx1a and Lim1/2 (D) or Islet1 (F). (I-L) Visualization of expression of Math1 (red) alone (I,K) and together with endogenous Lmx1a (green) (J,L) in E10.0 wild-type (I,J) and dr^J /dr^J embryos (K,L). In dr^J /dr^J, embryos, numerous Lmx1a/Math1-double-positive cells (yellow) are indicated by arrowheads.

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