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Fig. 7. Effect of downregulation of Bmp and Wnt signals on early roof plate development. Chick neural tubes expressing exogenous Noggin (A-E) and dnWnt1 (F-J) 18 hours after electroporation. Visualization of expression of roof plate markers Lmx1a (A,F) and MafB (C,H) (both red), Bmp4 (E,J) (blue) alone or together with GFP (green) (B,D,G,I). Arrowheads point to expression domains affected by overexpression of Noggin.





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