spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Effect of compromised PDGFA signaling on mesoderm movement. (A-R) In situ hybridization. Expression of Xbra at stage 10 (A-C) and stage 11.5 (G-J), and of chordin at stage 10 (D-F) and stage 11.5 (K-N), in uninjected embryos (A,D,G,K), and in embryos injected with dnPDGFA (B,E,H,L) or lfPDGFA mRNA (C,F,I,M) or PDGF morpholino (J,N). (A-C) Vegetal view. (D-N) Dorsovegetal view with animal towards the top. Brackets indicate extending notochord region. (O-R) Expression of gsc in controls (O), and in dnPDGFA (P), lfPDGFA (Q) and PDGF morpholino (R) gastrulae fixed at stage 12 and fractured mid-sagittally. Small arrowhead, blastopore lip; large arrowhead, tip of archenteron; arrow, gsc expression. (S-V) Convergent extension in dorsal blastopore lips explanted at stage 10 from control (S), dnPDGFA expressing (T), lfPDGFA overexpressing (U) and PDGF morpholino injected (V) gastrulae, fixed at stage 14 (n=15, three independent experiments for each treatment).





Right arrow Return to article