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Fig. 4. TAT-C3 treatment affects axonal morphology. The individual morphology of
neuronal processes from E12 explants could be visualized after GFP
electroporation. Control neurons showed straight axons (A), whereas
TAT-C3-treated neurons exhibited tortuous axons (B). For quantification
analysis, the trajectory of entire axons in control (C, n=11) and
TAT-C3 treated explants (E, n=11) was drawn, and the mean deviation
from a straight line measured (D). Data are presented using arbitrary units;
*P<0.001. Scale bar in A: 100 µm for A,B.
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