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Fig. 2. Luciferase expression detected in the diaphragm and liver after hepatic in utero delivery of rAAV2-CBA-Luc. At 15 days gestation, Gaa-/- fetuses were injected in the liver with 3x107 infectious particles of rAAV2-CBA-Luc. Animals were sacrificed at 1 month and assayed for luciferase expression. The highest levels of luciferase activity were detected in diaphragm (A) and liver (B). Black circles reflect values of individual samples; white and gray bars represent averages from saline-treated and rAAV2-treated samples, respectively. Diaphragm expression is plotted on a log scale.





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