spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 11. A model depicting the functional interactions between ER and mitochondria in the mouse egg. After Ca2+ is released from the ER into the cytosol via Ins(1,4,5)P3 receptors it can be taken up by the mitochondria. In the mitochondrial matrix, Ca2+ will stimulate the Kreb’s cycle as well as the electron transport chain and the F0/F1 synthase that phosphorylates ADP. ATP is then transported out of the mitochondria via the activity of the adenine nucleotide translocase (ANT) and the cytosolic ATP will be consumed by the SERCA pumps to restore the resting [Ca2+]c and refill the ER.





Right arrow Return to article