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Fig. 2. Expression of ß-galactosidase in Osr2 heterozygous embryos.
(A) At E9.5, ß-galactosidase expression (blue) was detected specifically
in the mesonephric vesicles (arrow). (B) At E10.5, ß-galactosidase
activity was detected in the mesonephros (arrow), in the limb buds, in the
maxillary and mandibular processes, in the mesenchyme posterior to the eye and
in the mesenchyme adjacent to the first branchial cleft (arrowhead). (C)
Facial view of a stained E10.5 embryo showing ß-galactosidase expression
in the palatal primordia (arrowheads). (D,E) Frontal sections of E13.5 (D) and
E14.75 (E) heterozygous embryos showing ß-galactosidase expression in the
palatal mesenchyme, olfactory mesenchyme, tooth bud mesenchyme, and the
periocular mesenchyme and the eyelids. e, eye; fl, forelimb bud; hl, hindlimb
bud; mb, mandibular process; mx, maxillary process; oe, olfactory epithelia;
p, palatal shelf, t, tongue; tb, tooth bud.
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