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Fig. 5. Contribution of the Dsh domains to the rescue of `canonical' features in
wg– embryos. (A'-E') Magnification of
the ventral side of the cuticle shown in A-E.
(A'',B'',C'',E'') Lateral views; (D'') dorsal view.
Cuticle (A-A') and En expression pattern (A'') of wild-type
embryos. (B-B'') wg– embryos show a short
cuticle (B) and a lawn of denticules on the ventral side (B'). The
expression in stripe of En in the lateral and dorsal ectoderm is lost, except
for very few cells (B''). Upon ubiquitous overexpression of Dsh
(C,C') or Dsh
DEP (D,D'), the length of the cuticle and the
presence of naked cuticle on the ventral side are rescued. A mild rescue of En
expression is observed in wg>da>Dsh embryos (C'') and to a
lesser extent in wg>da>DshDEP (D''). No rescue of
either the length of the cuticle (E), the presence of naked cuticle (E')
or the expression of En (E'') is observed after ubiquitous overexpression
of DshDIX. Moreover, the cuticle of wg>da>DshDIX
embryos is shorter than the cuticle of wg– embryos
(compare E with B).
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