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Fig. 7. Genome organization in tetrapod Otx2 locus. Locations of the 22
domains in Otx2 locus conserved among mouse, human and
Xenopus. Black bars in mouse and human Otx2 locus define the
locations of the nearest genes at the 5' and 3' sides,
respectively. Domains that exhibited enhancer activity are shown by red bars
[see Kurokawa et al. (Kurokawa et al.,
2004) for details of the analysis of the 3' region]. The
contiguous mapping is partial in the Xenopus Otx2 locus; however,
domains 
–
and 
–
exist in the genome. White
boxes indicate the Otx2-coding regions.
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