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Fig. 5. Expression of Fgf3 and Fgf10 in early feather
development. Detection of Fgf3 (A-C) or Fgf10 (D-F,J-L)
expression by whole-mount RNA in situ hybridization of embryos at HH28, before
the onset of feather placode development, and at HH30. (C,F) Expression of
Fgf3 and Fgf10 in embryos infected with RCAS-FGFR1-Fc and
RCAS-FGFR2-Fc at HH18. The nude region devoid of Fgf3 and
Fgf10 expression is included with a bracket. (G-I) Vibratome
sections, at the indicated positions, through the embryos shown in B, D and E,
respectively. Arrowheads in D indicate the stripes of Fgf10
expression in the region where bud development will be initiated. (J-L)
Expression of Fgf10 in the alar (J), pectoral (K) and tail tract (L).
Arrows indicate the feather tract, delineated by Fgf10 expression.
nt, neural tube.
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