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Fig. 4. When misexpressed with Vg1, both Chordin and Nodal can bypass the inhibition. A pellet of Vg1 was grafted into the lateral margin of a pre-streak stage embryo; 6 hours later, a second pellet of Vg1 and a pellet of either Chordin or Nodal were implanted together into the opposite side (A). In both cases (B,C) primitive streaks arise from both sides of the embryo.





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