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Fig. 8. Reduction of RPTP
function affects convergent extension.
RPTPmo embryos show shortening and broadening of the body axis
(yellow arrows in B,E), a characteristic of convergent extension mutants. This
effect is confirmed by using markers for the nascent notochord (A,D;
ntl, arrowheads), the boundaries of the neuroectoderm (B,E;
dlx3), the anteriormost prechordal plate hgg1 (hatching
gland gene 1; B,E) and somites (C,F; deltaC). (A-C)
Wild-type control embryos, (D-F) RPTPmo embryos. (G) Cycling
deltaC expression in the psm of wild-type and knypek
(kny) mutant embryos.