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Fig. 6. (A-D) RC2 immunostaining on coronal sections of mouse telencephalic
vesicles at E13 and P0. (A,C) Heterozygous animals; (B,D) Tenascin C
(TNC)-deficient animals. A reduction in the intensity of RC2 staining is
observed in the brains of TNC null animals at both ages, but note the normal
morphology of the processes at P0. (E) The percentage of RC2-positive cells in
dissociated cell populations from heterozygous and homozygous animals during
different stages of CNS development. Note the decrease in the proportion of
RC2+ cells in the homozygous animals at later stages, showing a reduction in
the number of radial glia. *P<0.05. c, cortex; s,
striatum; lv, lateral ventricle.
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