Supplemental Figure 1
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Fig. S1.
Expression of molecular markers in the dorsal spinal cords of wild-type and Lmx1b
mutant embryos at E11.5 and E12.5 detected by in situ hybridization. (A-D) Drg11 expression (arrows) in wild-type (A,C) and Lmx1b mutant (B,D) embryo at E11.5 (A,B) and E12.5 (C,D). Drg11 expression is lost from the onset of its expression.
(E-H) Ebf1 expression in
wild-type (E,G) and Lmx1b mutant
(F,H) embryos at E11.5 (E,F) and E12.5 (G,H). Ebf1 expression (arrows) is not changed at these stages.
(I-L) Ebf2 expression in
wild-type (I,K) and Lmx1b mutant
embryos (J,L) at E11.5 (I,J) and E12.5 (K,L). Ebf2 is downregulated at E12.5 (arrows). (M-P) Ebf3 expression in wild-type (M,O) and Lmx1b mutant (N,P) embryos at E11.5 (M,N) and E12.5 (O,P).
Ebf3 expression is weaker than
that of wild-type embryo at E12.5 (arrows). (Q-T) Rnx expression in wild-type (Q,S) and Lmx1b mutant (R,T) embryos at E11.5 (Q,R) and E12.5 (S,T).
Arrows indicate Rnx expression in
the dorsolateral spinal cord. Scale bars: 150 mm.
