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Fig. 4. eyg mediates the growth promoting function of Notch signaling. eyg¹/eyg^M3-12 mutants are eyeless with complete penetrance (see Fig. 1D). (A) In eyg¹, H^E31/eyg^M3-12 the eye size is partially restored. The eye size is also partially restored in (B) dpp-GAL4 UAS-N^act (abbreviated as dpP>N^act) and (C) dpp>Su(H) in the eyg¹/eyg^M3-12 mutant background. (D,E) When one copy of H was removed in eyg^M3-12, H^E31/eyg^M3-12, the flies have complete head structures but no eye (D) and eyg-lacZ (anti-ß-galactosidase, red) is detected in antennal discs, but not in eye discs (E). The disc is also stained with anti-DAC (green) to mark the antennal disc. (F) In ey>N^DN flies, the eye formation is completely inhibited. (G) When eyg and N^DN were co-expressed (ey>N^DN+eyg), the eye size was partially restored. (H) In ey>H flies, the eye formation is completely abolished. (I) In ey>H+eyg flies, the eye size is partially restored.

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